Harm Reduction Database
Know what you're
taking
Evidence-based information on 554+ substances. Dosages, duration, interactions, and safer use practices.
Popular Substances
View all →Cannabis
A common and widely used psychoactive plant, which is beginning to enjoy legal status for medical an...
LSD
LSD is a popular psychedelic with a relatively long history of use and research, and as such is know...
MDMA
The world's most popular empathogen with powerful pro-social effects. Has been strongly linked to co...
Ketamine
A short acting dissociative anaesthetic and hallucinogen commonly used in emergency medicine. It is ...
Cocaine
A highly popular, short acting CNS stimulant that works by blocking the reuptake of dopamine, seroto...
Everything you need
Comprehensive tools for informed decisions
Dosage Information
Threshold to heavy doses for multiple administration routes. Know your limits.
Combination Checker
Check interactions between substances. Identify dangerous combinations before mixing.
Safer Use Tips
Practical harm reduction advice from set & setting to emergency protocols.
Duration Timeline
Onset, peak, and aftereffects. Plan your experience with accurate timing.
Take it with you
Access everything offline. Track your experiences. Get help when needed.