4-PRO-MET

Description

4-PRO-MET (4-propionoxy-N-methyl-N-ethyltryptamine) is a synthetic tryptamine that chemically belongs to the so-called “classic psychedelics.” The compound is structurally closely related to psilocybin and psilocin, the active ingredients in magic mushrooms, as well as to the equally well-known 4-HO-MET (metocin) . It is often referred to in the scene as a kind of “legal psilocybin analogue” because its substituents (propionyl group) give it a similar basic structure to psilocybin. Use 4-PRO-MET is currently used primarily in chemical and pharmacological studies and in psychedelic research. As it is a new research chemical substance, there is currently little scientifically published data available on its pharmacology, safety, and long-term effects. Legal status Not explicitly listed in the BtMG (German Narcotics Act) in Germany and many other countries (as of 2025). However, it may fall under analogy or new psychoactive substances laws. Legal classification is subject to change at any time. Key chemical data Molecular formula: C₁₄H₂₀N₂O₂ Molecular weight: 248.32 g/mol Structure: Tryptamine skeleton with a 4-propionoxy substituent Related molecules Psilocybin (4-PO-DMT): naturally occurring prodrug of psilocin Psilocin (4-HO-DMT): active metabolite in psilocybin-containing mushrooms 4-HO-MET (metocin): known psilocin analog 4-ACO-DM.