Typical Dose 150-300 mg
Duration 20h - 37h
Interaction Risk Unknown
Detection Methods 1
Description
A frequently prescribed atypical antidepressant. Occasionally prescribed as an aid to smoking cessation. May lower seizure threshold in predisposed individuals. Poorly understood mechanism of action, probably an NDRI. Avoid combination with other drugs.
Effects & Dosing
Dosage
Oral
| Light | Common | Strong |
|---|---|---|
| - | 150-300 mg | 300-450 mg |
Duration
Metabolites
Total Duration 20h - 37h
Parent Compound
Total Duration 11h - 21h
Oral
Onset 15 min - 1h 30m
After Effects 1h - 6h
Safety & Risks
Safer Use
- Bupropion lowers the seizure threshold and can induce seizures when excessive doses are used and/or when combined with CNS stimulants or other drugs that also lower the threshold, such as theophylline, steroids, some tricyclic antidepressants, and alcohol
Detection Times
| Method | Detection Window |
|---|---|
| Urine | 2–4 days |
Note: Can cause false positives for amphetamines on some immunoassays.
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