💊
Typical Dose 150-300 mg
⏱️
Duration 20h - 37h
⚠️
Interaction Risk Unknown
🔬
Detection Methods 1
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Effect Profile

Describes the acute effect. This profile does not influence the OpenMind Score.

No effect profiles yet. Describe the acute effect without changing the long-term score.

Description

A frequently prescribed atypical antidepressant. Occasionally prescribed as an aid to smoking cessation. May lower seizure threshold in predisposed individuals. Poorly understood mechanism of action, probably an NDRI. Avoid combination with other drugs.

Effects & Dosing

Dosage

Oral

Light Common Strong
- 150-300 mg 300-450 mg

Duration

Metabolites

Total Duration 20h - 37h

Parent Compound

Total Duration 11h - 21h

Oral

Onset 15 min - 1h 30m
After Effects 1h - 6h
Safety & Risks

Safer Use

  1. Bupropion lowers the seizure threshold and can induce seizures when excessive doses are used and/or when combined with CNS stimulants or other drugs that also lower the threshold, such as theophylline, steroids, some tricyclic antidepressants, and alcohol

Detection Times

Method Detection Window
Urine 2–4 days

Note: Can cause false positives for amphetamines on some immunoassays.

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