Description
Caffeine is a a CNS stimulant, and also the most widely used psychoactive substance in the world. It is legal and unregulated in most parts of the world, and is found in many commonly sold products. It has a good safety profile, though regular heavy use can cause physical dependence and contribute to certain medical conditions.
Dosage
Oral
| Threshold | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| 10-20 mg | 20-75 mg | 75-250 mg | 250-400 mg | 400-400 mg+ |
Duration
Oral
Safer Use
- NOTE: The lethal dose for caffeine starts at approximately 3g. The average cup of coffee contains roughly 75-150mg of caffeine.
Detection Times
| Method | Detection Window |
|---|---|
| Blood | 12–24 hours |
| Urine | 1–2 days |
Note: Not part of any standard drug panel. Only tested in specific contexts (e.g., competitive sports at very high levels).
Interactions
26 known interactions with other substances.
High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating it may cause some physical discomfort.
Caffiene can bring out the natural stimulation from psychedelic drugs to make it uncomfortable. High doses can cause anxiety which is hard to handle while tripping
High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating the combination may cause some physical discomfort.
Details of this combination are not well understood but PCP generally interacts in an unpredictable manner.
This combination of stimulants is not generally necessary and may increase strain on the heart, as well as potentially causing anxiety and greater physical discomfort.
Caffiene is not really necessary with MDMA and increases any neurotoxic effects from MDMA
Both stimulants, risk of tachycardia, hypertension, and in extreme cases heart failure.
Everything in OpenMind
Track your use, check combinations and find safer use tips – even offline.