Description
Structurally related to Thiamine (vitamin B1), but with binding potential at the GABAa site, which causes it to produce effects most like those of a barbiturate: an effective sedative and hypnotic. Originally developed by Hoffman-LaRoche in the 1930s, it has seen use as a treatment for acute alcohol withdrawal.
Effects & Dosing
Dosage
Oral
| Threshold | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| 100-100 mg | 100-150 mg | 150-200 mg | - | 200-200 mg+ |
Duration
Oral
Onset 15 min - 40 min
Total Duration 5h - 8h
After Effects 1h - 16h
Safety & Risks
Safer Use
- The normal amount in capsules is 192mg's. Treat this more as a barbiturate than a benzodiazepine, as the toxicology for this substance is rather lacking.
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