Description
A highly popular, short acting CNS stimulant that works by blocking the reuptake of dopamine, serotonin, and norepinephrine. It is known to increase euphoria, confidence, sex-drive, focus, body temperature, and heart rate. Cocaine can cause severe vasoconstriction and is known to be cardiotoxic and have a high potential for compulsive redosing and addiction.
Dosage
Insufflated
| Light | Common | Strong | Heavy |
|---|---|---|---|
| 20-50 mg | 50-100 mg | 100-150 mg | 150-150 mg+ |
Duration
Oral
Safer Use
- NOTE: Depending on purity, dosage will vary
Detection Times
| Method | Detection Window |
|---|---|
| Blood | 12â24 hours |
| Saliva | 1â2 days |
| Urine | 2â4 days |
| Hair | 1â90 days |
Note: Part of standard 5-panel drug tests (SAMHSA). The primary metabolite benzoylecgonine is what is detected in urine. Heavy use may extend urine detection to 14 days.
Interactions
26 known interactions with other substances.
The combined stimulating effects of the two can lead to an uncomfortable body-load, while the focusing effects of cocaine can easily lead to thought loops. Coming down from cocaine while the DOx is still active can be quite anxiogenic
Cocaine and NBOMes both provide considerable stimulation. When combined they can result in severe vasoconstriction, tachycardia, hypertension, and in extreme cases heart failure.
Cocaine and 2c-t-x both provide considerable stimulation. When combined they can result in severe vasoconstriction, tachycardia, hypertension, and in extreme cases heart failure.
The anxiogenic and focusing effects of stimulants increase the chance of unpleasant thought loops. The combination is generally unnecessary because of the stimulating effects of psychedelics.
Both substances raise heart rate, in extreme cases, panic attacks caused by these drugs have led to more serious heart issues
This combination can easily lead to hypermanic states
Drinking on stimulants is risky because the sedative effects of the alcohol are reduced, and these are what the body uses to gauge drunkenness. This typically leads to excessive drinking with greatly reduced inhibitions, high risk of liver damage and increased dehydration. They will also allow you to drink past a point where you might normally pass out, increasing the risk. If you do decide to do this then you should set a limit of how much you will drink each hour and stick to it, bearing in mind that you will feel the alcohol less. Cocaine is potentiated somewhat by alcohol because of the formation of cocaethylene.
Stimulants increase respiration rate allowing a higher dose of opiates. If the stimulant wears off first then the opiate may overcome the patient and cause respiratory arrest.
Tramadol and stimulants both increase the risk of seizures.
This combination is poorly explored
Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences
The focus and anxiety caused by stimulants is magnified by psychedelics and results in an increased risk of thought loops
The anxiogenic and focusing effects of stimulants increase the chance of unpleasant thought loops. The combination is generally unnecessary because of the stimulating effects of psychedelics. Combination of the stimulating effects may be uncomfortable.
No unexpected interactions, though likely to increase blood pressure but not an issue with sensible doses. Moving around on high doses of this combination may be ill advised due to risk of physical injury.
Stimulants taken with MXE can lead to hypermanic states much more easily, especially if sleep is avoided.
This combination of stimulants will increase strain on the heart. It is not generally worth it as cocaine has a mild blocking effect on dopamine releasers like amphetamine
Cocaine blocks some of the desirable effects of MDMA while increasing the risk of heart attack.
Both stimulants, risk of tachycardia, hypertension, and in extreme cases heart failure.
Stimulants increase respiration rate allowing a higher dose of sedatives. If the stimulant wears off first then the opiate may overcome the patient and cause respiratory arrest. Likewise the G can wear off and leave a dangerous concentration of cocaine behind
Legal Status
This information is provided for educational purposes only and does NOT constitute legal advice. Laws change frequently and may vary by region, state, or municipality. Always verify the current legal status in your jurisdiction before making any decisions. Open Mind assumes no liability for the accuracy, completeness, or timeliness of this data.
Country Details Show 25 countries
CH Switzerland Illegal
Illegal controlled substance.
Switzerland has medically supervised drug consumption rooms in several cities where cocaine can be consumed, though possession and purchase remain illegal.
NL Netherlands Illegal
List I (hard drug) under the Opiumwet.
The Netherlands prosecutes cocaine as a List I (hard drug). Unlike cannabis, there is no gedoogbeleid (tolerance policy) for cocaine. Drug checking services (DIMS) do test cocaine samples for adulterants.
GB United Kingdom Illegal
Class A controlled substance. Maximum penalties.
Cocaine (including crack cocaine) is Class A in the UK. The UK has one of the highest cocaine usage rates in Europe. Crack cocaine carries the same classification as powder cocaine.
FR France Illegal
Illegal narcotic (stupéfiant).
France classifies cocaine as a narcotic (stupéfiant). Enforcement is strict, though drug consumption rooms exist in Paris and Strasbourg (primarily for opioid users).
BE Belgium Illegal
Illegal controlled substance.
Belgian cocaine enforcement is serious given Antwerp's role as a major European cocaine entry port. The port handles more cocaine seizures than any other in Europe.
PL Poland Illegal
Illegal narcotic substance (Group I-N).
Poland classifies cocaine in its most restricted narcotic group (I-N). No tolerance for personal use exists.
CA Canada Illegal
Schedule I under CDSA. Illegal for all non-medical purposes.
Cocaine is Schedule I in Canada with the most severe penalties. There are no decriminalization exceptions.
MX Mexico Illegal
Illegal. Personal use threshold: 500 mg.
Mexico's 2009 "Narcomenudeo" reform set a personal-use threshold of 500 mg for cocaine. This is roughly 3â5 lines/bumps, providing a meaningful buffer for personal users.
BR Brazil Illegal
Illegal. No fixed personal-use threshold.
Brazil is the world's second-largest cocaine consumer. The 2006 drug law eliminated prison for personal use but the user/trafficker distinction is racially biased in practice, disproportionately affecting Black and poor Brazilians.
AR Argentina Illegal
Illegal. The Arriola ruling provides limited protection for private use.
Cocaine use in Argentina is significant. The Arriola ruling technically protects private personal use from prosecution, but practical enforcement is inconsistent, especially outside Buenos Aires.
PE Peru Illegal
Cocaine: illegal. Coca leaf: legal and culturally protected.
Peru is the world's second-largest coca leaf producer. Coca leaf chewing (âcoqueoâ) is legal and culturally entrenched. ENACO holds the legal monopoly on coca leaf distribution. Personal cocaine possession (up to 2 g) is explicitly not a crime.
AU Australia Illegal
Illegal controlled substance. Severe penalties.
Australia has one of the highest cocaine prices in the world ($250â$400 AUD per gram) and among the highest per-capita usage. All states treat cocaine seriously.
NZ New Zealand Illegal
Class A controlled drug â the most severe category.
Cocaine is Class A in New Zealand but very uncommon due to geography and cost. Methamphetamine is a far more prevalent stimulant.
ZA South Africa Illegal
Banned substance (Schedule 7 + Drugs Act).
South Africa prohibits cocaine under both the Medicines Act and the Drugs and Drug Trafficking Act. Cocaine use is concentrated in urban centers.
IL Israel Illegal
Illegal dangerous drug.
Cocaine is a dangerous drug in Israel with no medical-use pathway or decriminalization initiatives.
JP Japan Illegal
Narcotic under the Narcotics and Psychotropics Control Law.
Japan classifies cocaine as a narcotic. The drug is relatively uncommon in Japan compared to stimulants like methamphetamine.
SG Singapore Illegal
Class A controlled drug. Trafficking above 30 g carries mandatory death penalty.
Singapore imposes the mandatory death penalty for trafficking of 30 g or more of cocaine. The presumption of trafficking kicks in at just 2 g of possession. This is among the most severe cocaine laws in the world.
DE Germany Medical Only
Anlage III of the BtMG â prescribable but highly restricted narcotic. Medical use in ENT surgery.
Germany uniquely places cocaine in Anlage III (prescribable) rather than Anlage I (non-prescribable). Cocaine is still occasionally used as a local anaesthetic in ENT surgery. The aggravated penalty threshold is 5 g of cocaine hydrochloride.
US United States Medical Only
Schedule II controlled substance. Recognized medical use (topical anaesthetic).
Cocaine is Schedule II (unlike MDMA/LSD which are Schedule I) because it retains accepted medical use as a topical anaesthetic. The crack vs powder cocaine sentencing disparity was reduced by the Fair Sentencing Act 2010 from 100:1 to 18:1, and further addressed by the EQUAL Act debates.
AT Austria Decriminalized
Suchtgift (narcotic). Personal use redirected to health system under "Therapie statt Strafe".
Austria's harm-reduction framework applies. Personal use is diverted to health authorities rather than criminal prosecution.
ES Spain Decriminalized
Private personal use is an administrative offense. Trafficking is a serious crime.
Spain treats cocaine as a "hard drug" for trafficking (sustancia que causa grave daño) with harsher penalties than cannabis, but personal private use remains decriminalized.
PT Portugal Decriminalized
Decriminalized for personal use (up to 2 g) under the 2001 reform.
Portugal's personal-use threshold for cocaine is 2 g. This is one of the more generous thresholds and has led to measurably reduced overdose deaths since 2001.
IT Italy Decriminalized
Tabella I substance. Personal use is an administrative offense.
Italy places cocaine in Tabella I. Personal use is not criminal. The quantity threshold for "personal use" is determined case by case.
CZ Czech Republic Decriminalized
Small amounts for personal use (up to 1 g) are a misdemeanor.
Czech Republic defines 1 g as the personal-use threshold for cocaine. Unlike cannabis or mushrooms, cocaine trafficking carries heavier penalties (2â10 years vs 1â5 years).
CO Colombia Decriminalized
Personal dose (1 g) decriminalized. Coca leaf is legally cultivated by indigenous communities.
Colombia has a uniquely complex relationship with cocaine. Personal use is constitutionally protected (C-221/94), and coca leaf chewing/cultivation by indigenous communities is legal. However, cocaine trafficking carries severe penalties and Colombia remains a major enforcement theater.
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