Cyclobenzaprine
Typical Dose 5-10 mg
Duration 6h - 12h
Interaction Risk Unknown
Detection Methods 2
Description
Muscle relaxant and CNS depressant used to relieve skeletal muscle spasms and associated pain in acute musculoskeletal conditions. Sometimes prescribed off-label for treatment of fibromyalgia or as a sleep aid. Has little recreational value alone, but may potentiate some opioids. May cause drowsiness, dry mouth and dizziness.
Effects & Dosing
Dosage
Oral
| Light | Common | Strong |
|---|---|---|
| 2-5 mg | 5-10 mg | 10-15 mg |
Duration
Oral
Onset 15 min - 45 min
Total Duration 6h - 12h
After Effects 1h - 6h
Safety & Risks
Safer Use
- Do not mix with other CNS depressants, or within two weeks of a MAOI.
Detection Times
| Method | Detection Window |
|---|---|
| Blood | 1–3 days |
| Urine | 3–8 days |
Note: Muscle relaxant structurally related to tricyclic antidepressants. Can cause false positives for tricyclic antidepressants (TCAs) on immunoassay.
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