💊
Typical Dose 200-400 mg
⏱️
Duration 6h - 8h
⚠️
Interaction Risk High
🔗
Combinations 26
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Detection Methods 1
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Description

Commonly found in certain over the counter cough medicines. Has dissociative effects similar to ketamine or MXE, though also shares properties with opioids and alcohol. Make sure DXM is the only active ingredient in the preparation.

Effects & Dosing

Dosage

Oral

Threshold Light Common Strong
75-100 mg 100-200 mg 200-400 mg 400-700 mg

Duration

Oral

Onset 20 min - 1h
Total Duration 6h - 8h
After Effects 1h - 12h
Safety & Risks

Safer Use

  1. NOTE: See http://dxm.tripsit.me for mg/lb doses, among other things. Deaths have been reported at 25mg/kg

Detection Times

Method Detection Window
Urine 2–4 days

Note: Can cause false positives for PCP on some immunoassays. Available over the counter as a cough suppressant.

Interactions

26 known interactions with other substances.

Dangerous 15
DOxNBOMes2C-T-xaMT5-MeO-xxTPCPAmphetaminesMDMACocaineAlcoholGHBOpioidsTramadolMAOIsSSRIs

The DOx class as psychedelic stimulants have the potential to mask the effects of DXM and could lead to redosing to an unsafe level. DXM can also potentiate DOx resulting in an unpleasantly intense experience.

Little information exists about this combination.

Both substances raise heart rate, in extreme cases, panic attacks caused by these drugs have led to more serious heart issues.

Both substances raise heart rate, in extreme cases, panic attacks caused by these drugs have led to more serious heart issues

Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. Place affected patients in the recovery position to prevent vomit aspiration from excess. Additionally CNS depression can lead to difficulty breathing. Avoid on anything higher than 1st plateau.

Both substances cause ataxia and bring a risk of vomiting and unconsciousness. If the patient falls unconscious while under the influence there is a severe risk of vomit aspiration if they are not placed in the recovery position. This combination is hard to predict

CNS depression, difficult breathing, heart issues, hepatoxic, just very unsafe combination all around. Additionally if one takes dxm, their tolerance of opiates goes down slightly, thus causing additional synergistic effects.

High risk of serotonin syndrome

High risk of serotonin syndrome.

⚠️ Caution 1
Benzodiazepines

Small doses of benzos can end a bad trip, but both substances potentiate the ataxia and sedation caused by the other and this can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position.

Low Risk 10
No Synergy

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