Fentanyl
Typical Dose 25-50 ug
Duration 1h - 4h
Interaction Risk Unknown
Detection Methods 3
Description
Fentanyl is a synthetic opiate analgesic with a rapid onset and short duration of action. It is a strong agonist at the μ-opioid receptors and is historically used to treat breakthrough pain. Fentanyl is approximately 100 times more potent than Morphine, and is commonly used as a patch. Sometimes used as an adulterant for heroin, which has led to many overdose deaths.
Effects & Dosing
Dosage
Insufflated
| Light | Common | Strong |
|---|---|---|
| 10-25 ug | 25-50 ug | 50-75 ug+ |
Duration
Buccal
Onset 15 min - 30 min
Total Duration 1h - 4h
Insufflated
Onset 5 min - 15 min
Total Duration 1h - 4h
Transdermal
Onset 1h 30m - 3h
Total Duration 48h - 72h
Safety & Risks
Safer Use
- NOTE: Due to Fentanyl's high potency, it is incredibly difficult to measure safely, and so can easily lead to overdose.
- Risk of post-acute withdrawal effects, including depression, anxiety disorder, psychosis, suicidal ideation in extreme cases.
Detection Times
| Method | Detection Window |
|---|---|
| Blood | 5–48 hours |
| Urine | 1–3 days |
| Hair | 1–90 days |
Note: Not detected by standard opiate immunoassay. Requires specific fentanyl testing. Detection window depends heavily on specific analogue.
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