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Typical Dose 200-300 mg
⏱️
Duration 6h - 12h
⚠️
Interaction Risk Moderate
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Combinations 26
🔬
Detection Methods 1
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Description

A psychedelic of the phenethylamine family. Found in psychedelic cacti that have long been used by peoples native to the Southwestern US and Mexico, including Peyote and San Pedro cacti, among others. Can be found as cactus pulp, as an extract from cacti, or as a synthetic substance created in a lab.

Effects & Dosing

Dosage

Oral

Light Common Strong
100-200 mg 200-300 mg 300-500 mg

Duration

Oral

Onset 1h - 3h
Total Duration 6h - 12h
After Effects 3h - 5h
Safety & Risks

Safer Use

  1. NOTE: Doses are for Mescaline HCl

Detection Times

Method Detection Window
Urine 2–3 days

Note: Not part of standard drug panels. Can cause false positives for amphetamines on some immunoassays.

Interactions

26 known interactions with other substances.

Dangerous 2

This combination can cause seizures due to the lowering of the threshold by tramadol and the potential of mescaline to cause seziures.

⚠️ Caution 9
DOxNBOMes2C-x2C-T-x5-MeO-xxTCannabisAmphetaminesCocaineMAOIs

The 5-MeO class of tryptamines can be unpredictable in their interactions

Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics.

The focus and anxiety caused by stimulants is magnified by psychedelics and results in an increased risk of thought loops

Low Risk 15
Decrease
AlcoholGHBBenzodiazepinesSSRIs
No Synergy
CaffeineOpioids

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