Midazolam
Typical Dose 10-15 mg
Duration 4h - 8h
Interaction Risk Unknown
Detection Methods 2
Description
A common hypnotic, sedative and anxiolytic benzodiazepine. High doses may cause amnesia and loss of inhibitions. Unusually, it is water soluble, and commonly used as a premedication for sedation as the solubility makes it better for IV use than other benzodiazepines.
Effects & Dosing
Dosage
Insufflated
| Light | Common | Strong |
|---|---|---|
| 3-7 mg | 7-15 mg | 15-25 mg |
Intramuscular
| Light | Common | Strong |
|---|---|---|
| 3-5 mg | 5-12 mg | 12-25 mg |
Intravenous
| Light | Common | Strong |
|---|---|---|
| 2.5-5 mg | 5-10 mg | 10-20 mg |
Oral
| Light | Common | Strong |
|---|---|---|
| 5-10 mg | 10-15 mg | 15-30 mg |
Rectal
| Light | Common | Strong |
|---|---|---|
| 3-7 mg | 7-15 mg | - |
Duration
Oral
Total Duration 4h - 8h
After Effects 1h - 12h
Safety & Risks
Safer Use
- All other CNS depressants.
Detection Times
| Method | Detection Window |
|---|---|
| Blood | 4–8 hours |
| Urine | 1–2 days |
Note: Very short-acting benzodiazepine. Rapid metabolism by CYP3A4.
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