Doxylamine
Typical Dose 200-350 mg
Duration 6h - 8h
Interaction Risk Unknown
Detection Methods 1
Community · single experiences
Effect Profile
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A first generation antihistamine and anticholinergic, originally used to treat nausea and itching, and later as a sleep aid. Causes drowsiness, and delirium in overdose. Sometimes used with opioids to combat nausea and potentiate effects.
Effects & Dosing
Dosage
Oral
| Threshold | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| 10-10 mg | 75-200 mg | 200-350 mg | - | 350-350 mg+ |
Duration
Oral
Onset 20 min - 30 min
Total Duration 6h - 8h
After Effects 1h - 6h
Safety & Risks
Safer Use
- As with other first generation antihistamines, if you take too much you could have a delirant like experience.
Detection Times
| Method | Detection Window |
|---|---|
| Urine | 1–3 days |
Note: OTC antihistamine/sleep aid. Not part of standard drug panels. May cause false positives for methadone or PCP on some immunoassays.
Community Experiences
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