Effect Profile
Describes the acute effect. This profile does not influence the OpenMind Score.
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Log inDescription
An antihistamine which, when taken in smaller doses relieves allergies and insomnia. In larger doses works as a deliriant and can actually keep the user awake. Generally the 'high' of this drug is reported as dysphoric, potentially causing hallucinations indistinguishable from reality.
Dosage
Oral
| Light | Common | Strong |
|---|---|---|
| 100-250 mg | 200-500 mg | 450-700 mg |
Duration
Oral
Safer Use
- NOTE: The doses provided are for recreational usage. For use as a sleep aid the dose ranges from 25-100mg, or as specified on the product packaging.
- Many oral diphenhydramine preparations contain analgesics such as acetaminophen/paracetamol or aspirin, which can be toxic to the liver in high doses.
Detection Times
| Method | Detection Window |
|---|---|
| Blood | 12–24 hours |
| Urine | 2–4 days |
Note: Diphenhydramine (Benadryl). Not part of standard drug panels. Has been reported to cause false positives for methadone or PCP on some immunoassays.
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