Typical Dose 200-500 mg
Duration 6h - 8h
Interaction Risk Unknown
Detection Methods 2
Description
An antihistamine which, when taken in smaller doses relieves allergies and insomnia. In larger doses works as a deliriant and can actually keep the user awake. Generally the 'high' of this drug is reported as dysphoric, potentially causing hallucinations indistinguishable from reality.
Effects & Dosing
Dosage
Oral
| Light | Common | Strong |
|---|---|---|
| 100-250 mg | 200-500 mg | 450-700 mg |
Duration
Oral
Onset 1h - 2h
Total Duration 6h - 8h
After Effects 1h - 12h
Safety & Risks
Safer Use
- NOTE: The doses provided are for recreational usage. For use as a sleep aid the dose ranges from 25-100mg, or as specified on the product packaging.
- Many oral diphenhydramine preparations contain analgesics such as acetaminophen/paracetamol or aspirin, which can be toxic to the liver in high doses.
Detection Times
| Method | Detection Window |
|---|---|
| Blood | 12–24 hours |
| Urine | 2–4 days |
Note: Diphenhydramine (Benadryl). Not part of standard drug panels. Has been reported to cause false positives for methadone or PCP on some immunoassays.
Everything in OpenMind
Track your use, check combinations and find safer use tips – even offline.