Description
A South African plant containing numerous psychoactive alkaloids, including mesembrine and mesembrenone. The first written account of the substance was in 1662. The pharmacology of these compounds is poorly understood, but they are suspected to be serotonin uptake inhibitors and potentially monoamine releasers. Said to suppress appetite, produce mild euphoria and reduce anxiety.
Effects & Dosing
Dosage
Oral
| Light | Common | Strong |
|---|---|---|
| 250-500 mg | 500-1000 mg | 1000-2000 mg |
Duration
Oral
Onset 30 min - 1h 30m
Total Duration 3h - 6h
After Effects 1h - 8h
Safety & Risks
Safer Use
- Note: We recommend against insufflating this substance, it is extremely painful and damaging to the nasal cavity.
- Other CNS depressants.
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